A review on dynamics of permeability-glycoprotein in efflux of chemotherapeutic drugs
Permeability-glycoprotein (P-gp) belongs to the ABS transporter protein family, with a high expression rate in cancerous cells. The substrate/inhibitors of the protein are structurally diverse, with no lucid mechanism of inhibition. There are two schools of thought on the inhibition mechanism: (i) P...
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Frontiers Media S.A.,
2024-04-01T00:00:00Z.
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