Genetic polymorphisms associated to folate transport as predictors of increased risk for acute lymphoblastic leukemia in Mexican children

• 主要な著者: Fausto Zaruma-Torres (著者), Ismael Lares-Asseff (著者), Verónica Loera-Castañeda (著者), Aurea Lima (著者), Aarón Reyes-Espinoza (著者), Martha Sosa-Macías (著者), Carlos Galaviz-Hernández (著者), María Cristina Arias-Pelaez (著者), Miguel Angel Reyes-López (著者), Luis Abel Quiñones (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2016-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Acute lymphoblastic leukemia (ALL) is a frequent neoplasia occurring in children. The most commonly used drug for the treatment of ALL is methotrexate (MTX), an anti-folate agent. Previous studies suggest that folate transporters play a role in ALL prognosis and that genetic polymorphism of genes en...