Granulocyte colony-stimulating factor and leukemogenesis

• Main Authors: Lorena Lobo de Figueiredo (Author), Rodrigo Siqueira de Abreu e Lima (Author), Eduardo Magalhães Rego (Author)
• Formato: Livro
• Publicado em: Hindawi Limited, 2004-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

THE granulocyte colony-stimulating factor (G-CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are activated. The cytoplasmic region proximal to the...