Sodium butyrate inhibits osteogenesis in human periodontal ligament stem cells by suppressing smad1 expression

• Main Authors: Jingyi Hou (Author), Junji Xu (Author), Yi Liu (Author), Haiping Zhang (Author), Sihan Wang (Author), Yao Jiao (Author), Lijia Guo (Author), Song Li (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Butyrate is a major subgingival microbial metabolite that is closely related to periodontal disease. It affects the proliferation and differentiation of mesenchymal stem cells. However, the mechanisms by which butyrate affects the osteogenic differentiation of periodontal ligamen...