Induction of apoptosis by Oleracein A and Oleracein B in HepG2 cancerous cells is mediated by ceramide generation, caspase-9/caspase-3 pathway activation, and oxidative damage

• Հիմնական հեղինակներ: Hamidreza Khodajou-Masouleh (Հեղինակ), Masoud Mashhadi Akbar Boojar (Հեղինակ), Sarah Khavari-Nejad (Հեղինակ), Gilda Karimi (Հեղինակ)
• Ձևաչափ: Գիրք
• Հրապարակվել է: Elsevier, 2022-03-01T00:00:00Z.
• Խորագրեր: article
• Առցանց հասանելիություն: Connect to this object online.

The present study aimed to discover whether oleracein A (OA) and oleracein B (OB) have anti-proliferative effects on HepG2 cell line and, if so, by which mechanisms they exert their effects. The results demonstrate that both OA and OB are independently able to decrease the viability of HepG2 cells i...