Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation

• मुख्य लेखकों: Satish Kumar (लेखक), Joanne E. Curran (लेखक), David C. Glahn (लेखक), John Blangero (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2016-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

A large number of EBV immortalized LCLs have been generated and maintained in genetic/epidemiological studies as a perpetual source of DNA and as a surrogate in vitro cell model. Recent successes in reprograming LCLs into iPSCs have paved the way for generating more relevant in vitro disease models...