Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation

• Main Authors: Satish Kumar (Author), Joanne E. Curran (Author), David C. Glahn (Author), John Blangero (Author)
• Formato: Livro
• Publicado em: Hindawi Limited, 2016-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

A large number of EBV immortalized LCLs have been generated and maintained in genetic/epidemiological studies as a perpetual source of DNA and as a surrogate in vitro cell model. Recent successes in reprograming LCLs into iPSCs have paved the way for generating more relevant in vitro disease models...