Human <it>PTCHD3 </it>nulls: rare copy number and sequence variants suggest a non-essential gene

• Main Authors: Lionel Anath C (Author), Moessner Rainald (Author), Lee-Ng Ka Ki M (Author), Kwan Benjamin YM (Author), Ghahramani Seno Mohammad M (Author), Marshall Christian R (Author), Scherer Stephen W (Author)
• Format: Book
• Published: BMC, 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Copy number variations (CNVs) can contribute to variable degrees of fitness and/or disease predisposition. Recent studies show that at least 1% of any given genome is copy number variable when compared to the human reference sequence...