Induction of ferroptosis promotes vascular smooth muscle cell phenotypic switching and aggravates neointimal hyperplasia in mice

• Main Authors: Shunchi Zhang (Author), Yanrou Bei (Author), Yueling Huang (Author), Yimin Huang (Author), Lianjie Hou (Author), Xi-Long Zheng (Author), Yiming Xu (Author), Shaoguo Wu (Author), Xiaoyan Dai (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Stent implantation-induced neointima formation is a dominant culprit in coronary artery disease treatment failure after percutaneous coronary intervention. Ferroptosis, an iron-dependent regulated cell death, has been associated with various cardiovascular diseases. However, the...