Activation of AMPK Enhances Neutrophil Chemotaxis and Bacterial Killing

• Main Authors: Dae Won Park (Author), Shaoning Jiang (Author), Jean-Marc Tadie (Author), William S. Stigler (Author), Yong Gao (Author), Jessy Deshane (Author), Edward Abraham (Author), Jaroslaw W. Zmijewski (Author)
• Format: Book
• Published: BMC, 2013-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract An inability of neutrophils to eliminate invading microorganisms is frequently associated with severe infection and may contribute to the high mortality rates associated with sepsis. In the present studies, we examined whether metformin and other 5' adenosine monophosphate-activated pr...