A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins

• Main Authors: Sarra El-Soussi (Author), Reine Hanna (Author), Hanna Semaan (Author), Amanda-Rose Khater (Author), Jad Abdallah (Author), Wassim Abou-Kheir (Author), Tamara Abou-Antoun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroblastoma is the most common extracranial nervous system tumor in children. It presents with a spectrum of clinical prognostic measures ranging from benign growths that regress spontaneously to highly malignant, treatment evasive tumors affiliated with increased mortality rates. MYCN amplificati...