Pluripotency-State-Dependent Role of Dax1 in Embryonic Stem Cells Self-Renewal

• Main Authors: Jianrong He (Author), Yuda Cheng (Author), Yan Ruan (Author), Jiali Wang (Author), Yanping Tian (Author), Jiaqi Wang (Author), Fengsheng Wang (Author), Chen Zhang (Author), Yixiao Xu (Author), Lianlian Liu (Author), Meng Yu (Author), Jiangjun Wang (Author), Binyu Zhao (Author), Yue Zhang (Author), Yi Yang (Author), Gaoke Liu (Author), Wei Wu (Author), Ping He (Author), Jiaxiang Xiong (Author), He Huang (Author), Junlei Zhang (Author), Rui Jian (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dax1(also known as Nr0b1) is regarded as an important component of the transcription factor network in mouse embryonic stem cells (ESCs). However, the role and the molecular mechanism of Dax1 in the maintenance of different pluripotency states are poorly understood. Here, we constructed a stable Dax...