Effect of ScLL and 15d-PGJ2 on viability and cytokine release in LPS-stimulated fibroblasts: an in vitro study

• Main Authors: Manuella Verdinelli de Paula REIS (Author), Gabriela Leite de SOUZA (Author), Priscilla Barbosa Ferreira SOARES (Author), Maria Aparecida de SOUZA (Author), Carlos José SOARES (Author), Camilla Christian Gomes MOURA (Author)
• Format: Book
• Published: Sociedade Brasileira de Pesquisa Odontológica, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This study evaluated the effect of a cyclopentenone-type PG, 15-Deoxy-Δ12,14-PG J2 (15d-PGJ2), and lectin (ScLL) on the viability of human gingival fibroblasts (HGFs), and on IL-6 and TGFβ-1 release by these fibroblasts, stimulated with lipopolysaccharide (LPS). HGFs were stimulated with LP...