SPDEF suppresses head and neck squamous cell carcinoma progression by transcriptionally activating NR4A1

• Main Authors: Yanting Wang (Author), Xianyue Ren (Author), Weiyu Li (Author), Ruoyan Cao (Author), Suyang Liu (Author), Laibo Jiang (Author), Bin Cheng (Author), Juan Xia (Author)
• Format: Book
• Published: Nature Publishing Group, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract SAM pointed domain containing E26 transformation-specific transcription factor (SPDEF) plays dual roles in the initiation and development of human malignancies. However, the biological role of SPDEF in head and neck squamous cell carcinoma (HNSCC) remains unclear. In this study, the express...