Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells

• Main Authors: Laura Gallego-Yerga (Author), Inmaculada Posadas (Author), Cristina de la Torre (Author), Jesús Ruiz-Almansa (Author), Francesco Sansone (Author), Carmen Ortiz Mellet (Author), Alessandro Casnati (Author), José M. García Fernández (Author), Valentín Ceña (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Giant amphiphiles encompassing a hydrophilic β-cyclodextrin (βCD) component and a hydrophobic calix[4]arene (CA4) module undergo self-assembly in aqueous media to afford core-shell nanospheres or nanocapsules, depending on the nanoprecipitation protocol, with high docetaxel (DTX) loading capacity. T...