TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway

• Main Authors: Huijia Fu (Author), Wang Tan (Author), Zhi Chen (Author), Zi Ye (Author), Yuhan Duan (Author), Jiayu Huang (Author), Hongbo Qi (Author), Xiru Liu (Author)
• Format: Book
• Published: BMC, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Successful implantation is a complex process that is influenced by embryo quality, endometrial receptivity, immune factors, and the specific type of in vitro fertilization protocol used. DNA topoisomerase IIα (TOP2A) is a well-known protein involved in cell proliferation; however...