The impact of CYP2D6*41 on CYP2D6 enzyme activity using phenotyping methods in urine, plasma, and saliva

• Main Authors: Ye Jin (Author), Shuquan Zhang (Author), Pei Hu (Author), Xin Zheng (Author), Xiaoduo Guan (Author), Rui Chen (Author), Shuyang Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: The CYP2D6*41 variant is the second or third frequent reduced function allele in Chinese with a frequency of around 3-4%, while it is the major reduced function allele in Indians, Saudi Arabians and Caucasians with frequencies of around 10-20%. The present study was designed to explore the imp...