Enhanced Wound Healing- and Inflammasome-Associated Gene Expression in TNFAIP3-Interacting Protein 1- (TNIP1-) Deficient HaCaT Keratinocytes Parallels Reduced Reepithelialization

• Auteurs principaux: Rambon Shamilov (Auteur), Tyler W. Ackley (Auteur), Brian J. Aneskievich (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2020-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

TNIP1 protein is a widely expressed, cytoplasmic inhibitor of inflammatory signaling initiated by membrane receptors such as TLRs which recognize pathogen-associated and damage-associated molecular patterns (PAMPs and DAMPs). Keratinocyte TNIP1 deficiency sensitizes cells to PAMPs and DAMPs promotin...