The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation

• Main Authors: Haixia Xu (Author), Xiao Du (Author), Geng Liu (Author), Shuang Huang (Author), Wenya Du (Author), Sailan Zou (Author), Dongmei Tang (Author), Chen Fan (Author), Yongmei Xie (Author), Yuquan Wei (Author), Yan Tian (Author), Xianghui Fu (Author)
• Format: Book
• Published: Elsevier, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The mixed lineage kinase domain like (MLKL) protein, receptor interacting protein (RIPK) 1, and RIPK3 are key regulators of necroptosis, a highly pro-inflammatory mode of cell death that has been implicated in various pathological processes and human diseases. However, the role of these n...