Nanobody-based CAR-T cells for cancer immunotherapy

• Main Authors: Pouya Safarzadeh Kozani (Author), Abdolhossein Naseri (Author), Seyed Mohamad Javad Mirarefin (Author), Faeze Salem (Author), Mojtaba Nikbakht (Author), Sahar Evazi Bakhshi (Author), Pooria Safarzadeh Kozani (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Chimeric antigen receptor T-cell (CAR-T) therapy is the result of combining genetic engineering-based cancer immunotherapy with adoptive cell therapy (ACT). CAR-T therapy has been successful in treating various types of hematological cancers. CARs are receptors made of an extracellular doma...