C2CD4B Evokes Oxidative Stress and Vascular Dysfunction via a PI3K/Akt/PKCα-Signaling Pathway

• Main Authors: Paola Di Pietro (Author), Angela Carmelita Abate (Author), Valeria Prete (Author), Antonio Damato (Author), Eleonora Venturini (Author), Maria Rosaria Rusciano (Author), Carmine Izzo (Author), Valeria Visco (Author), Michele Ciccarelli (Author), Carmine Vecchione (Author), Albino Carrizzo (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High glucose-induced endothelial dysfunction is an important pathological feature of diabetic vasculopathy. While genome-wide studies have identified an association between type 2 diabetes mellitus (T2DM) and increased expression of a C2 calcium-dependent domain containing 4B (C2CD4B), no study has...