Long‐term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice

• Main Authors: Anna Carolina Zaia Rodrigues (Author), María Laura Messi (Author), Zhong‐Min Wang (Author), Henry Jacob Bonilla (Author), Willard M. Freeman (Author), Osvaldo Delbono (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The discovery of adrenoceptors, which mediate the effects of the sympathetic nervous system neurotransmitter norepinephrine on specific tissues, sparked the development of sympathomimetics that have profound influence on skeletal muscle mass. However, chronic administration has s...