Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing

• Main Authors: Daniel Felipe Silgado-Guzmán (Author), Mariana Angulo-Aguado (Author), Adrien Morel (Author), María José Niño-Orrego (Author), Daniel-Armand (Author), Nora Constanza Contreras Bravo (Author), Carlos Martin Restrepo (Author), Oscar Ortega-Recalde (Author), Dora Janeth Fonseca-Mendoza (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In genes related to drug pharmacokinetics, molecular variations determine interindividual variability in the therapeutic efficacy and adverse drug reactions. The assessment of single-nucleotide variants (SNVs) is used with growing frequency in pharmacogenetic practice, and recently, high-throughput...