A plant protein signal sequence improved humoral immune response to HPV prophylactic and therapeutic DNA vaccines

• Main Authors: Silvia Massa (Author), Francesca Paolini (Author), Gianfranca Curzio (Author), Marcelo Nazario Cordeiro (Author), Elena Illiano (Author), Olivia Costantina Demurtas (Author), Rosella Franconi (Author), Aldo Venuti (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Signal sequences (ss) play a critical role in the sorting of nascent secretory and membrane proteins. This function has been conserved from bacteria through eukaryotes, although ss appear diverse in length and amino acid composition. Sorting of proteins is also critical to instruct antigens for a pr...