Palmitoleic Acid (N-7) Attenuates the Immunometabolic Disturbances Caused by a High-Fat Diet Independently of PPARα

• Main Authors: Camila O. Souza (Author), Alexandre A. S. Teixeira (Author), Edson A. Lima (Author), Helena A. P. Batatinha (Author), Lara M. Gomes (Author), Milena Carvalho-Silva (Author), Isabella T. Mota (Author), Emilio L. Streck (Author), Sandro M. Hirabara (Author), José C. Rosa Neto (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Palmitoleic acid (PMA) has anti-inflammatory and antidiabetic activities. Here we tested whether these effects of PMA on glucose homeostasis and liver inflammation, in mice fed with high-fat diet (HFD), are PPAR-α dependent. C57BL6 wild-type (WT) and PPAR-α-knockout (KO) mice fed with a standard die...