Ponatinib Induces a Procoagulant Phenotype in Human Coronary Endothelial Cells via Inducing Apoptosis

Ponatinib Induces a Procoagulant Phenotype in Human Coronary Endothelial Cells via Inducing Apoptosis

BCR-ABL tyrosine kinase inhibitors (TKIs) are effective drugs in the treatment of patients with chronic myeloid leukemia. However, based on clinical studies, ponatinib was associated with the development of thrombotic complications. Since endothelial cells (ECs) regulate blood coagulation, their abn...

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Main Authors: Bálint Krajcsir (Author), Marianna Pócsi (Author), Zsolt Fejes (Author), Béla Nagy (Author), János Kappelmayer (Author), Ildikó Beke Debreceni (Author)
Format: Book
Published: MDPI AG, 2024-04-01T00:00:00Z.
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