Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl4-) Induced Liver Injury in Mice

• Главные авторы: Sura Wanessa Santos Rocha (Автор), Maria Eduarda Rocha de França (Автор), Gabriel Barros Rodrigues (Автор), Karla Patrícia Sousa Barbosa (Автор), Ana Karolina Santana Nunes (Автор), André Filipe Pastor (Автор), Anne Gabrielle Vasconcelos Oliveira (Автор), Wilma Helena Oliveira (Автор), Rayana Leal Almeida Luna (Автор), Christina Alves Peixoto (Автор)
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• Опубликовано: Hindawi Limited, 2014-01-01T00:00:00Z.
• Предметы: article
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This study investigated the anti-inflammatory effects of DEC on the CCl4-induced hepatotoxicity in C57BL/6 mice. Chronic inflammation was induced by i.p. administration of CCl4 0.5 μL/g of body weight through two injections a week for 6 weeks. DEC (50 mg/kg) was administered by gavage for 12 days be...