Can the TLR-4-Mediated Signaling Pathway Be "A Key Inflammatory Promoter for Sporadic TAA"?

• Main Authors: Giovanni Ruvolo (Author), Calogera Pisano (Author), Giuseppina Candore (Author), Domenico Lio (Author), Cesira Palmeri (Author), Emiliano Maresi (Author), Carmela R. Balistreri (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Thoracic aorta shows with advancing age various changes and a progressive deterioration in structure and function. As a result, vascular remodeling (VR) and medial degeneration (MD) occur as pathological entities responsible principally for the sporadic TAA onset. Little is known about their genetic...