Can the TLR-4-Mediated Signaling Pathway Be "A Key Inflammatory Promoter for Sporadic TAA"?

• मुख्य लेखकों: Giovanni Ruvolo (लेखक), Calogera Pisano (लेखक), Giuseppina Candore (लेखक), Domenico Lio (लेखक), Cesira Palmeri (लेखक), Emiliano Maresi (लेखक), Carmela R. Balistreri (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2014-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Thoracic aorta shows with advancing age various changes and a progressive deterioration in structure and function. As a result, vascular remodeling (VR) and medial degeneration (MD) occur as pathological entities responsible principally for the sporadic TAA onset. Little is known about their genetic...