Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion
Objective: Glucagon-like peptide-1 is a nutrient-sensitive hormone secreted from enteroendocrine L cells within the small and large bowel. Although GLP-1 levels rise rapidly in response to food ingestion, the greatest density of L cells is localized to the distal small bowel and colon. Here, we asse...
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Format: | Book |
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Elsevier,
2020-07-01T00:00:00Z.
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A1234.567 |
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