A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study

• Main Authors: Kailong Ji (Author), Wei Liu (Author), Weihang Yin (Author), Xiangrong Kong (Author), Honghong Xu (Author), Zeng-Wei Lai (Author), Jing-Ya Li (Author), Jian-Min Yue (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new class of potent liver injury protective compounds, phychetins A−D (1−4) featuring an unique 6/6/5/6/5 pentacyclic framework, were isolated and structurally characterized from a Chinese medicinal plant Phyllanthus franchetianus. Compounds 2−4 are three pairs of enantiomers that were initially o...