Next-generation Sequencing and Karyotype Analysis for the Diagnosis of Robertsonian Translocation Type Trisomy 13: A Case Report

• Main Authors: Jing SHA (Author), Fumin LIU (Author), Bei ZHANG (Author), Yang HUANG (Author), Qinglin ZHANG (Author), Gao JUAN (Author), Jingfang ZHAI (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trisomy 13 (Patau syndrome) is the third most common autosomal trisomy with a prevalence between 1 in 10,000 - 20,000 live births. Robertsonian translocations represent the largest number of chromosomal aberrations in human population with an incidence of 1.23 in 1000 live birth and translocation 13...