Biphasic Effect of Pirfenidone on Angiogenesis

• Main Authors: Donghao Gan (Author), Wenxiang Cheng (Author), Liqing Ke (Author), Antonia RuJia Sun (Author), Qingyun Jia (Author), Jianhai Chen (Author), Zhanwang Xu (Author), Juan Xu (Author), Peng Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pirfenidone (PFD), a synthetic arsenic compound, has been found to inhibit angiogenesis at high concentrations. However, the biphasic effects of different PFD concentrations on angiogenesis have not yet been elucidated, and the present study used an in vitro model to explore the mechanisms underlyin...