B1 cells protect against Schistosoma japonicum-induced liver inflammation and fibrosis by controlling monocyte infiltration.

• Main Authors: Liang Yong (Author), Yuanyuan Tang (Author), Cuiping Ren (Author), Miao Liu (Author), Jijia Shen (Author), Xin Hou (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During Schistosoma infection, lack of B cells results in more severe granulomas, inflammation, and fibrosis in the liver, but the mechanisms underlying this pathology remain unclear. This study was to clarify the mechanisms underpinning the immunomodulation of B cells in mice infected with Schistoso...