Pretreatment of Sialic Acid Efficiently Prevents Lipopolysaccharide-Induced Acute Renal Failure and Suppresses TLR4/gp91-Mediated Apoptotic Signaling

Background/Aims: Lipopolysaccharides (LPS) binding to Toll-like receptor 4 (TLR4) activate NADPH oxidase gp91 subunit-mediated inflammation and oxidative damage. Recognizing the high binding affinity of sialic acid (SA) with LPS, we further explored the preventive potential of SA pretreatment on LPS...

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Main Authors: Shih-Ping Hsu (Author), Chin-Chih Chen (Author), Chiang-Ting Chien (Author)
Format: Book
Published: Karger Publishers, 2016-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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