Proposing a framework to quantify the potential impact of pharmacokinetic drug-drug interactions caused by a new drug candidate by using real world data about the target patient population

Proposing a framework to quantify the potential impact of pharmacokinetic drug-drug interactions caused by a new drug candidate by using real world data about the target patient population

Abstract Drug development teams must evaluate the risk/benefit profile of new drug candidates that perpetrate drug-drug interactions (DDIs). Real‐world data (RWD) can inform this decision. The purpose of this study was to develop a predicted impact score for DDIs perpetrated by three hypothetical dr...

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Main Authors: Simon Dagenais (Author), Christine Lee (Author), Carol Cronenberger (Author), Ellen Wang (Author), Vaishali Sahasrabudhe (Author)
Format: Book
Published: Wiley, 2024-03-01T00:00:00Z.
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