Proposing a framework to quantify the potential impact of pharmacokinetic drug-drug interactions caused by a new drug candidate by using real world data about the target patient population

• मुख्य लेखकों: Simon Dagenais (लेखक), Christine Lee (लेखक), Carol Cronenberger (लेखक), Ellen Wang (लेखक), Vaishali Sahasrabudhe (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2024-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Drug development teams must evaluate the risk/benefit profile of new drug candidates that perpetrate drug-drug interactions (DDIs). Real‐world data (RWD) can inform this decision. The purpose of this study was to develop a predicted impact score for DDIs perpetrated by three hypothetical dr...