Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation

• Main Authors: Dinesh M Bramhane (Author), Preethi A Kulkarni (Author), Elvis A.F Martis (Author), Raghuvir R. S Pissurlenkar (Author), Evans C Coutinho (Author), Mangal S Nagarsenker (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: The objective of present study was to study the influence of different β-cyclodextrin derivatives and different methods of complexation on aqueous solubility and consequent translation in in vivo performance of Pioglitazone (PE). Material and Methods: Three cyclodextrins: β-cyclodextrin (BCD),...