Amorphous Solid Dispersions (ASDs): The Influence of Material Properties, Manufacturing Processes and Analytical Technologies in Drug Product Development

• Main Authors: Raman Iyer (Author), Vesna Petrovska Jovanovska (Author), Katja Berginc (Author), Miha Jaklič (Author), Flavio Fabiani (Author), Cornelius Harlacher (Author), Tilen Huzjak (Author), Manuel Vicente Sanchez-Felix (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Poorly water-soluble drugs pose a significant challenge to developability due to poor oral absorption leading to poor bioavailability. Several approaches exist that improve the oral absorption of such compounds by enhancing the aqueous solubility and/or dissolution rate of the drug. These include ch...