Risk of candidiasis associated with interleukin-17 inhibitors: A real-world observational study of multiple independent sources

• Главные авторы: Linda Davidson (Автор), Juul M.P.A. van den Reek (Автор), Mariolina Bruno (Автор), Florence van Hunsel (Автор), Ron M.C. Herings (Автор), Vasiliki Matzaraki (Автор), Collins K. Boahen (Автор), Vinod Kumar (Автор), Hans M.M. Groenewoud (Автор), Frank L. van de Veerdonk (Автор), Mihai G. Netea (Автор), Elke M.G.J. de Jong (Автор), Bart Jan Kullberg (Автор)
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• Опубликовано: Elsevier, 2022-02-01T00:00:00Z.
• Предметы: article
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Summary: Background: Biologics directed against the T-helper (Th)-17 pathway have been approved for several inflammatory diseases. Interleukin (IL)-17 is involved in anti-Candida host defense, and clinical trials suggested increased candidiasis incidence during IL-17 inhibitor therapy. We describe t...