Trypanocidal activity of genotoxic concentration of benznidazole on epimastigote forms of Trypanosoma cruzi = Atividade tripanocida da concentração genotóxica do benzonidazol em formas epimastigotas de Trypanosoma cruzi

• Main Authors: Edilson Nobuyoshi Kaneshima (Author), Marialba Avezum Alves Castro-Prado (Author), Max Jean de Ornelas Toledo (Author), Silvana Marques Araújo (Author), Mônica Lúcia Gomes (Author)
• Format: Book
• Published: Universidade Estadual de Maringá, 2012-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The genotoxicity of benznidazole at a concentration of 75 µM, used in the treatment of Chagas' disease, has been recently reported. The present study evaluated the inhibitory effect of benznidazole on the growth of epimastigote forms of T. cruzi I and II by using genotoxic (75 µM) and non-genot...