Mammalian Animal and Human Retinal Organ Culture as Pre-Clinical Model to Evaluate Oxidative Stress and Antioxidant Intraocular Therapeutics

• Main Authors: Martina Kropp (Author), Mohit Mohit (Author), Cristina Ioana Leroy-Ciocanea (Author), Laura Schwerm (Author), Nina Harmening (Author), Thais Bascuas (Author), Eline De Clerck (Author), Andreas J. Kreis (Author), Bojan Pajic (Author), Sandra Johnen (Author), Gabriele Thumann (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress (OS) is involved in the pathogenesis of retinal neurodegenerative diseases such as age-related macular degeneration (AMD) and diabetic retinopathy (DR) and an important target of therapeutic treatments. New therapeutics are tested in vivo despite limits in terms of transferability a...