Tumor-targeting intravenous lipid emulsion of paclitaxel: Characteristics, stability, toxicity, and toxicokinetics

• Main Authors: Jun Ye (Author), Lin Li (Author), Jiye Yin (Author), Hongliang Wang (Author), Renjie Li (Author), Yanfang Yang (Author), Yongbiao Guan (Author), Xuejun Xia (Author), Yuling Liu (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipid nanoemulsions are promising nanodrug delivery carriers that can improve the efficacy and safety of paclitaxel (PTX). However, no intravenous lipid emulsion of PTX has been approved for clinical treatment, and systemic safety profiles have not yet been reported. Here we outline the development...