CD8+ T Cell-Mediated Immunity during Trypanosoma cruzi Infection: A Path for Vaccine Development?

• Main Authors: Fernando dos Santos Virgilio (Author), Camila Pontes (Author), Mariana Ribeiro Dominguez (Author), Jonatan Ersching (Author), Mauricio Martins Rodrigues (Author), José Ronnie Vasconcelos (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MHC-restricted CD8+ T cells are important during infection with the intracellular protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. Experimental studies performed in the past 25 years have elucidated a number of features related to the immune response mediated by these T c...