Low-Level Laser Treatment Induces the Blood-Brain Barrier Opening and the Brain Drainage System Activation: Delivery of Liposomes into Mouse Glioblastoma

• Main Authors: Oxana Semyachkina-Glushkovskaya (Author), Denis Bragin (Author), Olga Bragina (Author), Sergey Socolovski (Author), Alexander Shirokov (Author), Ivan Fedosov (Author), Vasily Ageev (Author), Inna Blokhina (Author), Alexander Dubrovsky (Author), Valeria Telnova (Author), Andrey Terskov (Author), Alexander Khorovodov (Author), Daria Elovenko (Author), Arina Evsukova (Author), Maria Zhoy (Author), Ilana Agranovich (Author), Elena Vodovozova (Author), Anna Alekseeva (Author), Jürgen Kurths (Author), Edik Rafailov (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The progress in brain diseases treatment is limited by the blood-brain barrier (BBB), which prevents delivery of the vast majority of drugs from the blood into the brain. In this study, we discover unknown phenomenon of opening of the BBBB (BBBO) by low-level laser treatment (LLLT, 1268 nm) in the m...