Sulforaphane Inhibits MGO-AGE-Mediated Neuroinflammation by Suppressing NF-κB, MAPK, and AGE-RAGE Signaling Pathways in Microglial Cells

• Main Authors: Lalita Subedi (Author), Jae Hyuk Lee (Author), Bhakta Prasad Gaire (Author), Sun Yeou Kim (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2020-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Advanced glycation end products (AGEs) are produced through the binding of glycated protein or lipid with sugar, and they are known to be involved in the pathogenesis of both age-dependent and independent neurological complications. Among dicarbonyl compounds, methylglyoxal (MGO), which is produced...