Satisfying QTPP of Erythropoietin Biosimilar by QbD through DoE-Derived Downstream Process Engineering

• Main Authors: Kakon Nag (Author), Enamul Haq Sarker (Author), Samir Kumar (Author), Sourav Chakraborty (Author), Maksusdur Rahman Khan (Author), Mashfiqur Rahman Chowdhury (Author), Rony Roy (Author), Ratan Roy (Author), Bipul Kumar Biswas (Author), Emrul Hasan Bappi (Author), Mohammad Mohiuddin (Author), Naznin Sultana (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Well-characterized and scalable downstream processes for the purification of biologics are extremely demanding for delivering quality therapeutics to patients at a reasonable price. Erythropoietin (EPO) is a blockbuster biologic with diverse clinical applications, but its application is limited to f...