Development and Optimization of Luliconazole Spanlastics to Augment the Antifungal Activity against <i>Candida albicans</i>

• Main Authors: Nabil A. Alhakamy (Author), Mohammed W. Al-Rabia (Author), Shadab Md (Author), Alaa Sirwi (Author), Selwan Saud Khayat (Author), Sahar Saad AlOtaibi (Author), Raghad Abkar Hakami (Author), Hadeel Al Sadoun (Author), Basmah Medhat Eldakhakhny (Author), Wesam H. Abdulaal (Author), Hibah M. Aldawsari (Author), Shaimaa M. Badr-Eldin (Author), Mahmoud A. Elfaky (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Luliconazole is a new topical imidazole antifungal drug for the treatment of skin infections. It has low solubility and poor skin penetration which limits its therapeutic applications. In order to improve its therapeutic efficacy, spanlastics nanoformulation was developed and optimized using a combi...