Norfloxacin Loaded Lipid Polymer Hybrid Nanoparticles for Oral Administration: Fabrication, Characterization, In Silico Modelling and Toxicity Evaluation

• Main Authors: Muhammad Asghar Khan (Author), Shahzeb Khan (Author), Mohsin Kazi (Author), Sultan M. Alshehri (Author), Muhammad Shahid (Author), Shafi Ullah Khan (Author), Zahid Hussain (Author), Muhammad Sohail (Author), Muhammad Shafique (Author), Hajra Afeera Hamid (Author), Mahwish Kamran (Author), Abdelbary Elhissi (Author), Muhammad Wasim (Author), Hnin Ei Thu (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Norfloxacin (NOR), widely employed as an anti-bacterial drug, has poor oral bioavailability. Nano based drug delivery systems are widely used to overcome the existing oral bioavailability challenges. Lipid-Polymer Hybrid Nanoparticles (LPHNs) exhibit the distinctive advantages of both polymeric and...