Preclinical study and clinical trial of a novel therapeutic vaccine against multi-drug resistant tuberculosis

• Main Authors: Masaji Okada (Author), Yoko Kita (Author), Satomi Hashimoto (Author), Hitoshi Nakatani (Author), Shiho Nishimastu (Author), Yumiko Kioka (Author), Yasuko Takami (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

[Purpose] Multi-drug resistant (MDR), Mycobacterium tuberculosis (TB) is a big problem in the world. We have developed novel TB therapeutic vaccine (HVJ-E/HSP65 DNA +IL-12 DNA). [Methods and Results] DNA vaccine expressing TB heat shock protein 65 and IL-12 was delivered by the hemagglutinating viru...