Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway

• 主要な著者: Yuan Zhou (著者), Jinfa Huang (著者), Lingling Zeng (著者), Qian Yang (著者), Fangjuan Bai (著者), Qiqing Mai (著者), Kaixian Deng (著者)
• フォーマット: 図書
• 出版事項: BMC, 2024-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Chemotherapy exposure has become a main cause of premature ovarian insufficiency (POI). This study aimed to evaluate the role and molecular mechanism of human umbilical cord mesenchymal stem cell-derived exosomes (hUMSC-Exos) in ovarian function protection after chemotherapy. Met...