Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Egile Nagusiak: Ožbej Zupančič (Egilea), Josip Matić (Egilea), Aygün Doğan (Egilea), Alessio Gaggero (Egilea), Johannes Khinast (Egilea), Amrit Paudel (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...